Assessing TD-GC-MS/MS for the Measurement of PFAS in Air and From Consumer ProductsAir Monitoring, Methods, and Technology
Oral Presentation
Presented by C. Widdowson
Prepared by H. Calder1, L. Miles1, E. Fausett2
1 - Markes International, 1000B Central Park, Western Avenue, Bridgend, (State/Province), CF31 3RT, United Kingdom
2 - Agilent Technologies, 2850 Centerville Rd., Wilmington, Delaware, 19808, United States
Contact Information: [email protected]; 01443230935
ABSTRACT
Per- and polyfluoroalkyl substances (PFAS) remain a critical focus in environmental and public health research. Analytical chemists continue to refine monitoring techniques for diverse matrices and emerging priority species as understanding of sources and their impact grows.
To date studies and methods for volatile PFAS compounds remain limited. The term "volatile PFAS" encompasses a wide range of compounds, from fluorotelomer alcohols (FTOHs) to freons. In recent toxicological studies there is a suggestion that the potential to cause harm from classes such as FTOHS is equal to or greater than their better cousins such as perfluorocarboxylic acids (PFCAs). This underscores the need for robust monitoring strategies.
Volatile PFAS are often precursor compounds used in the manufacture of consumer products and polymers. To date their presence has been detected in atmospheric and indoor air, soil gas, workplace environments, industrial emissions and a wide variety of consumer products from cookware to make up. The diverse nature of these sample types presents challenges for expanding research and analytical services.
Thermal desorption gas chromatography-tandem mass spectrometry (TD-GC-MS/MS) provides a versatile approach for sampling various matrices and analyzing multiple target species while minimizing background interference. With specialized accessories for sampling air, materials, and industrial sources, this technique offers a powerful and practical solution for comprehensive PFAS monitoring.
This presentation will evaluate the overall performance of TD-GC-MS/MS, including its detection limits, robustness, and repeatability. Data from real-world samples will demonstrate its capability to monitor PFAS from multiple sources effectively.
