Rapid, Efficient and High-Throughput Extraction Method of PFAS from Tissue and Soil

Polyfluoroalkyl Substances (PFAS) in the Environment
Poster Presentation

Prepared by A. Stell, B. Fessler, B. Liu
CEM Corporation, 3100 Smith Farm Rd., Matthews, NC, 28106, United States

Contact Information: [email protected]; 704-821-7015


There is increasing concern of per- and polyfluoroalkyl substances (PFAS) in our environment as a whole, due to their persistent nature. More and more regulation regarding PFAS is being implemented. Having a harmonized method to accurately determine the PFAS content in tissue, soil, as well as other solid matrices, is important to this industry. Further, the number of samples and sample types that laboratories are analyzing is rapidly growing. The extraction of PFAS can be challenging given the susceptibly to contamination and the low levels in which these compounds are present. Existing techniques are predominately manual methods that are not rapid, simple, and efficient. In this study, a high-throughput extraction system, that uses microwave technology is explored as an alternative to traditional PFAS sample preparation techniques. This method offers efficient extraction of PFAS from solid matrices in a batch format in under an hour. Excellent extraction recovery and reproducibility of PFAS from tissue and soil samples is presented. This batch microwave system method offers a rapid, simple, and efficient solution for PFAS testing that can easily be integrated into any laboratories’ workflow.