Managing Doubly Charged Rare Earth Element Interferences in SQ & QQQ ICP-MS

Operational Issues Impacting the Environmental Laboratory Industry
Oral Presentation

Prepared by C. Jones
Agilent Technologies, Inc., 5301 Stevens Creek Blvd, Santa Clara, CA, 95051, United States

Contact Information: [email protected]; 408-203-8677


Of the three types of spectroscopic interference in ICP-MS (polyatomic, isobaric, and doubly-charged), doubly-charged are becoming of concern as more interest in the use of rare earth elements (REE’s) for high technology devices, mining of these REE’s potentially allows for increased introduction into various water sources, soils and uptake by plant materials.
Collision/reaction cell (CRC) technology has successfully reduced most polyatomic interferes, isobaric interferences may be avoided using alternate isotopes, in most cases doubly-charged can also be avoided using alternate isotopes as well. However, in some cases, no isotope exists that is completely free of doubly-charged interferences.
This presentation will discuss the procedures to correct for doubly-charged interferences using equations with half mass correction using single quad ICP-MS and the utilization of triple quad ICP-MS technology using reactive gases to eliminate the bias when doubly-charged elements are present.