Validation Studies of EPA Method 1633 for Monitoring PFAS With a Triple Quadrupole Mass Spectrometry

Polyfluoroalkyl Substances (PFAS) in the Environment
Poster Presentation

Prepared by T. Astill
PerkinElmer, 2443 Trent St, Victoria, BC, V8R4Z4, Canada

Contact Information: [email protected]; 604-376-6499


Per- and polyfluoroalkyl substances (PFAS) are a group of man-made chemicals that have been used in a wide variety of industries around the world since the 1950s. Applications include food packaging, various household products, fire suppression foams, and water repellent clothing. This class of chemicals are incredibly stable so they are persistent and accumulate in the environment. Growing health concerns regarding PFASs and their prevalence in consumer goods and the environment indicates a critical need to monitor levels of PFAS in the environment. EPA Method 1633 is currently one of the standard methods for analysis of PFASs to measure low parts per trillion of 40+ PFAS compounds.. This presentation will focus on validation of EPA Method 1633 using the PerkinElmer QSight LC-MS/MS