Results and Learnings from Automating the SPE Procedure of EPA Method 1633

Polyfluoroalkyl Substances (PFAS) in the Environment
Poster Presentation

Prepared by I. Wan
PromoChrom Technologies, 13351 Commerce Parkway, Unit 1103, Richmond, British Columbia, V6V 2X7, Canada

Contact Information: [email protected]; 778-723-0421


Solid Phase Extraction (SPE) is employed by EPA draft Method 1633 for the extraction of PFAS across 8 different sample matrices. When performed manually, the SPE procedure requires multiple handling steps and constant monitoring of liquid flow. Special requirements for sample preparation, extraction and clean up further adds to the challenges for laboratories when bringing on this method. Automation and optimization of the SPE procedure is critical for achieving good quality results and releasing laboratory workers from labor-intensive routines.

The SPE-03 8-Channel system is developed collaboratively with numerous PFAS labs over the years, spanning EPA Methods 537.1, 533 and 1633. Currently it is being used for the multi-lab validation as well as running field samples with draft Method 1633. This presentation will share the experience and data obtained while working with some of these PFAS labs. It is expected that the learnings will foster wider understanding and discussion of this method.