Evaluation of a New Polymeric Weak Anion Exchange Solid Phase Extraction Sorbent for PFAS

Polyfluoroalkyl Substances (PFAS) in the Environment
Oral Presentation

Prepared by M. Giardina1, M. Juck1, T. Anumol1, F. Moingeon2, M. Kamuf3, J. Caldwell4, S. Choi4, M. Mandell4M. Giardina5, M. Juck5, T. Anumol5
1 - Agilent Technologies, 2850 Centerville Rd, Wilmington, DE, 19808, United States
2 - Agilent Technologies UK Ltd., Essex Road, Church Stretton, Shropshire, SY6 6AX, United Kingdom
3 - Agilent Technologies Deutschland GmbH, Hewlett-Packard-Str. 8, Waldbronn, 76337, Germany
4 - Agilent Technologies, Inc., 91 Blue Ravine Rd, Folsom, CA, 95630-4714, United States
5 - Agilent Technologies, 2850 Centerville Rd, Wilmington, DE, 19808, United States

Contact Information: [email protected]; 302-636-8211


Weak anion exchange (WAX) solid phase extraction (SPE) has emerged as the sorbent of choice for the extraction of PFAS in many environmental applications and regulated methods. Functionalized polymeric WAX is generally preferred over a unfunctionalized polymer in order to exploit the specific ionic interaction that occur between the acidic PFAS and basic polymeric ligand. This has been a key development toward improved recovery of the short chain PFAS (i.e. U.S. EPA Method 533). However, as the number of targets of interest have increased, analytes with a broader range of functional groups need to be considered. The success of a new polymeric WAX for PFAS must take into account the ever-increasing diversity of PFAS targets. In this presentation, the development of a new polymeric WAX for PFAS is explored in detail for the extraction of over 60 target compounds comprising varying subclasses. Critical attributes such as target recovery, sorbent cleanliness, and the strength of the WAX mechanism compared to other polymeric WAX sorbents will be discussed.