Accelerated Solvent Extraction of Airborne Per- and Polyfluoroalkyl Substances from Styrene-Divinylbenzene Resin

Air Monitoring, Methods, and Technology
Oral Presentation

Prepared by J. Hoisington
Restek Corporation, 110 Benner Circle, Bellefonte, PA, 16823, United States

Contact Information: [email protected]; 1-800-356-1688 ext 2473


PFAS (perfluoro alkyl substances) are a class of chemical compounds with many industrial applications, including non-stick surfaces, rain-repellent fabrics, electronics, and many others. They have been linked to several human health problems, such as cancer, thyroid disease, and pregnancy issues. Due to their inert nature, they are very stable in the environment and have the potential to bio-accumulate.

Testing for PFAS has mainly focused on water matrices, but more recently, attention has been directed to potential sources of PFAS in air. The EPA has recently released OTM-45, a research method for large volume air sampling using styrene-divnylbenzene resin and liquid impingers, followed by Soxhlet extraction and LC-MS-MS analysis. This presentation provides an alternative method for extraction using Accelerated Solvent Extraction (ASE). This has the potential to reduce the time and solvent use needed to extract the PFAS samples, allowing labs to have greater throughput and produce less waste.