A Consolidated Method for the Analysis of Organochlorine Pesticides and Polychlorinated Biphenyls in Environmental Samples using Automated SPE and GC-MS/MS

Crafting Consensus Methods for Environmental Sampling and Measurement
Oral Presentation

Prepared by M. MacLennan1, K. Hope1, I. Wan2
1 - Pacific Rim Laboratories, Inc., #103, 19575 55A Ave, Surrey, BC, V3S 8P8, Canada
2 - Promochrom, 12180 Horseshoe Way Unit 6, Richmond, BC, V7A 4V5, Canada

Contact Information: [email protected]; 778-835-2439


Both EPA Method 608.3 and Method 625.1 are used to determine organochlorine pesticides (OCP) and polychlorinated biphenyls (PCB) in industrial discharge and other environmental samples. Although Method 608.3 utilizes a halogen-specific (HSD) detection approach, GC/MS in Method 625.1 is cited as an alternative detection approach. The proposed method aims to utilize GC/MS/MS to offer better selectivity and sensitivity over HSD. Additionally, Methods 608.3 and 625.1 only provide the steps for liquid-liquid extraction (LLE) but allow for other clean-up approaches including solid-phase extraction that can reduce extraction time, solvent usage and human involvement. Recent advances in automated SPE, the development of novel solid phases and the increasing use of GC/MS/MS highlight the need for a more consolidated method directed at the simultaneous analysis of OCP and PCB, whose development is described herein.