Perchlorate Quantitation in Drinking water by a Novel Modular Ion Chromatograph Coupled with Single Quadrupole Mass Spectrometry

Drinking Water
Poster Presentation

Prepared by H. Guo1, R. Marfil-Vega2
1 - Shimadzu Scientific Instruments, 7102 Riverwood Drive, Columbia, Maryland, 21046, United States
2 - Shimadzu scientific, 7102 Riverwood Drive, Columbia, Maryland, 21046, United States

Contact Information: [email protected]; 410-910-0985


Work for regulating perchlorate in drinking water at Federal level has been on-going for almost a decade. The Environmental Protection Agency published in summer of 2019 a proposed rulemaking to establish a Maximum Contaminant Level for this chemical. A few perchlorate determination methods have been developed by the U.S. EPA. EPA Method 332.0 is one of the most sensitive methods using suppressed ion chromatography coupled with mass spectrometry. In this study, an IC-MS method was developed using the LC-MS 2020 single quadrupole MS with a novel electrolytically regenerated anion suppressor as a part of a modular IC system to determine perchlorate in drinking water. The system produced linear response with coefficient of determination greater than 0.999 from concentration of 0.5 ppb to 10 ppb. This study demonstrated that the robust and reliable performance of the novel modular IC-MS for the determination of perchlorate in EPA Methods 332.0.