Modified Sample Clean-up for Combined POPs Using Automated Multi-Column Fractionation and Analytical Optimization
Oral Presentation
Prepared by T. Hall, P. Bassignani
FMS, Inc, 580 Pleasant Street, Watertown, MA, 02038, United States
Contact Information: [email protected]; 617-744-8467
ABSTRACT
Analysis of Priority Organic Pollutants (POPs) often require complex, multi faceted clean-up procedures for low level analysis, including HRMS and tandem quadrapole MS. Traditionally separated as separate samples for independent analysis, the combination of samples often leads to complications with analyte separations and/or concentration variations. The utilization of automated, multi-column clean-ups in conjunction with optimization of analytical practices can overcome these problems, and result in streamlined sample prep for a variety of analyses. Analytes examined include PCDDs, PCDFs, PCBs, PBDEs, PCNs and OCPs to be combined in a single extract with optimized clean-up. Experimental trials on sorbent optimization, sample amounts and extract final and injection volumes are all variables of focus.
Oral Presentation
Prepared by T. Hall, P. Bassignani
FMS, Inc, 580 Pleasant Street, Watertown, MA, 02038, United States
Contact Information: [email protected]; 617-744-8467
ABSTRACT
Analysis of Priority Organic Pollutants (POPs) often require complex, multi faceted clean-up procedures for low level analysis, including HRMS and tandem quadrapole MS. Traditionally separated as separate samples for independent analysis, the combination of samples often leads to complications with analyte separations and/or concentration variations. The utilization of automated, multi-column clean-ups in conjunction with optimization of analytical practices can overcome these problems, and result in streamlined sample prep for a variety of analyses. Analytes examined include PCDDs, PCDFs, PCBs, PBDEs, PCNs and OCPs to be combined in a single extract with optimized clean-up. Experimental trials on sorbent optimization, sample amounts and extract final and injection volumes are all variables of focus.
