Large Volume Injection (LVI) for GC: Dos; Don’ts; Whys; Won’ts
Oral Presentation
Prepared by R. Brown, C. Neslund
Eurofins Lancaster Laboratories Environmental, LLC, 2425 New Holland Pike, Lancaster, PA, 17601, United States
Contact Information: [email protected]; 717-656-2300
ABSTRACT
Analytical laboratories routinely evaluate existing analytical methods to determine what improvements can be implemented that will result in lower detection limits. Over the last several years, one technique in the field of gas chromatography (GC) that has been intensely investigated is Large Volume Splitless Injection (LVI). Injecting a larger sample extract volume than has historically been used – in some cases 25x – 50x more – has resulted in maintaining and, in many cases, lowering of detection limits, as well as reductions in sample and toxic solvent volumes needed for extractions. These benefits have created a “greener” scenario in the analytical chemistry arena than was previously the case. Real world examples will be presented which demonstrate reasons why a lab would want to consider this change in procedure, the challenges faced along the road, and the benefits that can be achieved with implementation of the technique.
Oral Presentation
Prepared by R. Brown, C. Neslund
Eurofins Lancaster Laboratories Environmental, LLC, 2425 New Holland Pike, Lancaster, PA, 17601, United States
Contact Information: [email protected]; 717-656-2300
ABSTRACT
Analytical laboratories routinely evaluate existing analytical methods to determine what improvements can be implemented that will result in lower detection limits. Over the last several years, one technique in the field of gas chromatography (GC) that has been intensely investigated is Large Volume Splitless Injection (LVI). Injecting a larger sample extract volume than has historically been used – in some cases 25x – 50x more – has resulted in maintaining and, in many cases, lowering of detection limits, as well as reductions in sample and toxic solvent volumes needed for extractions. These benefits have created a “greener” scenario in the analytical chemistry arena than was previously the case. Real world examples will be presented which demonstrate reasons why a lab would want to consider this change in procedure, the challenges faced along the road, and the benefits that can be achieved with implementation of the technique.
