Combined Fluorotelomer Alcohol/8270 Analysis Using GC-MS/MS

Per- and Polyfluoroalkyl Substances (PFAS) in the Environment
Poster Presentation

Prepared by J. Hoisington, E. Pack, T. Reed
Restek Corporation, 110 Benner Circle, Bellefonte, PA, 16823, United States


Contact Information: [email protected]; 1-814-353-1300

ABSTRACT

The analysis of PFAS compounds in environmental samples has traditionally focused on ionic, non-volatile PFAS analyzed by LC-MS/MS. Many PFAS compounds, such as the fluorotelomer alcohols (FTOH), are neutral and semi-volatile and can be better analyzed by GC-MS/MS. While no EPA methods have been published, labs have analyzed these compounds with a variety of preparation techniques and column selections, including liquid/liquid extractions, headspace, and sorbent-based extractions on both volatile and semi-volatile type columns.
In this presentation we’ll explore a combined 8270/FTOH method, focusing on small volume liquid/liquid extractions and GC-MS/MS using the new RMX-5Sil MS column. This workflow would allow labs to incorporate neutral PFAS compounds into their existing semi-volatile workflows, streamlining laboratory operations.